Methaqualone CAS: 72-44-6 tranquilizer hypnotic

Mequinone yog hypnotic sedative.Nws yog muag raws li hom xws li Quaalude (/ KOMp peb Ua Qauv d/KWAY-lood) thiab Sopor, uas muaj 300 mg ntawm methaqualone, thiab nyob rau hauv lub npe hom Mandrax ua ib tug ua ke tshuaj, Nws muaj 250 milligrams ntawm mequinone thiab 25. milligrams ntawm diphenhydramine nyob rau hauv tib ntsiav tshuaj, feem ntau nyob rau hauv cov teb chaws Europe.Kev lag luam ntau lawm ntawm mequinone raug txiav tawm hauv nruab nrab-1980s vim muaj kev tsim txom thiab kev quav yeeb quav tshuaj.Nws yog ib pawg tswv cuab ntawm quinazolinone.

Cov teebmeem sedative thiab hypnotic ntawm mequinone tau pom thawj zaug hauv xyoo 1955. Xyoo 1962, Wallace thiab Tiernan tau txais US patent rau mequinone.Nws siv peaked nyob rau hauv thaum ntxov 1970s raws li ib tug kev kho mob rau insomnia thiab raws li ib tug sedative thiab nqaij relaxant.

Mequinone tau loj hlob hauv kev muaj koob npe raws li cov tshuaj lom neeg ua si thiab cov yeeb yaj kiab hauv lub sijhawm xyoo 1960 thiab 1970s, thiab raug xa mus rau "ludes" lossis "disco ncuav qab zib" [tsim xav tau] vim nws siv dav hauv xyoo 1970s disco craze, Los yog "sopers" (tseem hu ua "soaps") hauv Tebchaws Meskas thiab Canada, thiab "mandraks" thiab "mandies" hauv tebchaws United Kingdom, Australia, thiab New Zealand.Cov tshuaj yog muag nyob rau hauv daim ntawv ntawm dawb bases thiab ntsev (hydrochloride).Qhov kev siv no txhais tau hais tias cov tshuaj tau tswj hwm hauv ntau lub tebchaws / thaj chaw thiab yog li ntawd poob rau hauv United Nations Convention on Psychotropic Substances