Nimetazepam CAS: 2011-67-8 hypnotic tranquilizer

Nimetazepam yog qhov nruab nrab ua haujlwm hypnotic, benzodiazepine derivative.Nws tau tsim thawj zaug hauv xyoo 1964 los ntawm pab pawg ntawm Hoffmann-La Roche.Nws muaj zog hypnotic, tiv thaiv kev ntxhov siab, calming thiab skeletal leeg so los.Nimetazepam kuj yog ib qho tshuaj tiv thaiv kab mob tshwj xeeb.Nws yog muag raws li ib tug 5-milligram ntsiav tshuaj hu ua Erimin, lub npe hom tsim thiab muag los ntawm Sumitomo, ib tug loj Japanese tuam txhab.Nyiv yog tib lub tebchaws hauv ntiaj teb uas tsim cov tshuaj nimetazepam.Sab nraum Nyiv Pooj Teb, Erimin muaj nyob rau hauv feem ntau ntawm East thiab Southeast Asia thiab yog dav siv raws li ib tug luv luv kev kho mob rau cov neeg uas muaj insomnia loj heev uas pom nws nyuaj rau pw tsaug zog los yog pw tsaug zog.Sumitomo tau tso tseg tsis ua Erimin txij thaum lub Kaum Ib Hlis 2015. Nws tseem muaj nyob rau hauv cov khoom lag luam lossis Lavol.

Nimetazepam tau dav siv nyob rau hauv 1980s thiab 1990s, tshwj xeeb tshaj yog nyob rau hauv Nyiv, Malaysia, Brunei, Philippines, Thaib, Indonesia, Hong Kong thiab Singapore.Nrog kev tsim txom thiab kev quav yeeb quav tshuaj, cov ntawv sau tshuaj rau cov tshuaj tau poob qis txij li xyoo 2005. Nws yog siv los ua cov tshuaj tiv thaiv rau menyuam yaus.Nws tseem yog tseem siv nyob rau hauv feem ntau hnyav thiab debilitating mob ntawm insomnia nyob rau hauv inpatient Settings los yog luv luv-term outpatient kho.Rau lub hom phiaj no, cov tshuaj tsaug zog benzodiazepines Esazolam thiab nitrazepam tau siv ntau dua li nitrazepam.Antidepressants xws li trazodone thiab mirtazapine los yog Zopiclone thiab zolpidem yog thawj kab tshuaj rau insomnia.

Txawm hais tias cov tshuaj ntawm nimetazepam tau txo qis, kev tsim txom ntawm cov tshuaj tseem nyob hauv Brunei, Singapore, Malaysia thiab Philippines.Nws yog feem ntau siv ua ke nrog methamphetamine thiab ecstasy, nrog rau cov tshuaj opioids (tshwj xeeb tshaj yog heroin lossis morphine).Nimetazepam raug txwv nruj raws li kev cai lij choj hauv Malaysia, uas tau ua rau cov tshuaj tsis txaus, tab sis ntau cov tshuaj muag hauv khw dub raws li lub npe Nimetazepam yog cuav.Diazepam thiab nitrazepam yog cov feem ntau siv benzodiazepines hauv cheeb tsam, thiab yog li ntawd, lawv feem ntau hloov thiab muag hauv khw dub, feem ntau yog nitrazepam.

Kev tsim khoom tsis raug cai ntawm Nimezepam (muag raws li Erimin-5) yog thoob plaws hauv cheeb tsam.Kev tsim txom ntawm nimetazepam txuas ntxiv mus ntxiv thoob plaws xyoo 2010s.Kev qaug dab peg ntawm kev tsim khoom tsis raug cai Erimin-5 ntsiav tshuaj coincided nrog methamphetamine qaug dab peg hauv Malaysia.Ib tug me me ntawm 46 qhov tsis raug cai Erimin-5 ntsiav tshuaj tau ntes tau raug kuaj rau lawv lub cev thiab tshuaj lom neeg.Cov khoom xyaw nquag, dopant, thawj diluent, thiab zas xim yog cov yam ntxwv ntawm cov ntsiav tshuaj.Cov txiaj ntsig tau pom tias Nimetazepam yog cov khoom xyaw nquag tshaj plaws hauv feem coob ntawm cov ntsiav tshuaj uas tau ntes.Lactose tau kuaj pom tias yog lub ntsiab diluent hauv feem ntau cov qauv, ua raws li mannitol thiab tom qab ntawd dicalcium phosphate dihydrate.Sunset daj tau pom nyob rau hauv feem ntau cov qauv tshuaj, siv ib leeg los yog ua ke nrog lwm yam dyes (xws li tartar thiab Lichenol 4R) muab cov ntsiav tshuaj ib tug txiv duaj / txiv kab ntxwv xim.Cov ntsiav tshuaj ntsuab nyob rau hauv cov qauv muaj ci xiav thiab tartar dyes.Diazepam feem ntau yog cov tshuaj tiv thaiv kev ntxhov siab thiab yog cov khoom muaj nyob hauv tsuas yog ib qho ntawm 46 ntsiav tshuaj.Nitrazepam, muaj zog sedative thiab hypnotic thiab niam txiv tshuaj ntawm nitrazepam, tau pom tias yog ib qho kev sib txuas, nrog caffeine yog cov khoom tseem ceeb ua ke hauv peb ntsiav tshuaj.

Xyoo 2003, Singapore txeeb tau 94,200 Erimin-5 ntsiav tshuaj.Lub chaw soj nstuam ntawm Central Narcotics Board (CNB) tau ua qhov kev sim ntawm cov ntsiav tshuaj thiab cov txiaj ntsig tau lees paub tias lawv yog nitrazepam tiag tiag.